ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Synonyms:
BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3
Species:
Human ITGA2B (3674), Mouse Itga2b (16399), Rat Itga2b (685269), domestic guinea pig Itga2b (100727374), naked mole-rat Itga2b (101714332), Horse ITGA2B (100009697), cow ITGA2B (515011), sheep ITGA2B (101115719), Zebrafish itga2b (445380), domestic cat ITGA2B (101100930)
UniProtKB ID:
Gene ID:
- Human(3674) Summary: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
- Mouse(16399) integrin alpha 2b
- Rat(685269) integrin, alpha 2B
- domestic guinea pig(100727374) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- naked mole-rat(101714332) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- Horse(100009697) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- cow(515011) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- sheep(101115719) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- Zebrafish(445380) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
- domestic cat(101100930) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- dog(403789) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Milli-Mark® Anti-CD41-FITC Antibody, clone 5B12, clone 5B12, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry
Anti-Integrin αIIb Antibody, cytoplasmic domain, serum, Chemicon®,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
immunoprecipitation (IP)
Small Molecule - Inhibitor
Product Number
Description
Species