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Merck

IRF5

interferon regulatory factor 5

Synonyms:
SLEB10
Species:
UniProtKB ID:
Gene ID:
  • Human(3663) Summary: This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010]
  • Mouse(27056) interferon regulatory factor 5
  • Rat(296953) interferon regulatory factor 5
  • naked mole-rat(101713015) interferon regulatory factor 5
  • domestic guinea pig(100731125) interferon regulatory factor 5
  • Domestic Rabbit(100350244) interferon regulatory factor 5
  • sheep(101105408) interferon regulatory factor 5
  • cow(615340) interferon regulatory factor 5
  • domestic cat(101082480) interferon regulatory factor 5
  • chicken(430409) interferon regulatory factor 5
  • Zebrafish(405811) interferon regulatory factor 5
  • dog(482264) interferon regulatory factor 5
  • Horse(100071786) interferon regulatory factor 5

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