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Merck

IRF1

interferon regulatory factor 1

Synonyms:
IRF-1, MAR
Species:
Human IRF1 (3659), Mouse Irf1 (16362), Rat Irf1 (24508), domestic guinea pig Irf1 (100719575), domestic cat IRF1 (101095633), Domestic Rabbit IRF1 (100328724), sheep IRF1 (443136), cow IRF1 (337917), cow IRF1 (789216), naked mole-rat Irf1 (101719873) ...More
UniProtKB ID:
P10914, Q96GG7
Gene ID:
  • Human(3659) Summary: IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008]
  • Mouse(16362) interferon regulatory factor 1
  • Rat(24508) interferon regulatory factor 1
  • domestic guinea pig(100719575) interferon regulatory factor 1
  • domestic cat(101095633) interferon regulatory factor 1
  • Domestic Rabbit(100328724) interferon regulatory factor 1
  • sheep(443136) interferon regulatory factor 1
  • cow(337917) interferon regulatory factor 1
  • cow(789216) interferon regulatory factor 1
  • naked mole-rat(101719873) interferon regulatory factor 1
  • dog(481500) interferon regulatory factor 1
  • chicken(396384) interferon regulatory factor 1

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