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Merck

IRAK3

interleukin-1 receptor-associated kinase 3

Synonyms:
ASRT5, IRAKM
Species:
Human IRAK3 (11213), Mouse Irak3 (73914), Rat Irak3 (314870), Zebrafish irak3 (567444), dog IRAK3 (481150), domestic cat IRAK3 (101093197), cow IRAK3 (510342), naked mole-rat Irak3 (101704873), sheep IRAK3 (101115273), domestic guinea pig Irak3 (100729478)
UniProtKB ID:
Q9Y616, B4DQ57
Gene ID:
  • Human(11213) Summary: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
  • Mouse(73914) interleukin-1 receptor-associated kinase 3
  • Rat(314870) interleukin-1 receptor-associated kinase 3
  • Zebrafish(567444) interleukin-1 receptor-associated kinase 3
  • dog(481150) interleukin-1 receptor-associated kinase 3
  • domestic cat(101093197) interleukin-1 receptor-associated kinase 3
  • cow(510342) interleukin-1 receptor-associated kinase 3
  • naked mole-rat(101704873) interleukin-1 receptor-associated kinase 3
  • sheep(101115273) interleukin-1 receptor-associated kinase 3
  • domestic guinea pig(100729478) interleukin-1 receptor-associated kinase 3

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