IL2RB
interleukin 2 receptor, beta
Synonyms:
CD122, IL15RB, P70-75
Species:
Human IL2RB (3560), Mouse Il2rb (16185), Rat Il2rb (25746), sheep IL2RB (101107088), dog IL2RB (403439), domestic cat IL2RB (101092622), naked mole-rat Il2rb (101726369), Zebrafish il2rb (793920), domestic guinea pig Il2rb (100730639)
UniProtKB ID:
Gene ID:
- Human(3560) Summary: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]
- Mouse(16185) interleukin 2 receptor, beta chain
- Rat(25746) interleukin 2 receptor, beta
- sheep(101107088) interleukin 2 receptor, beta
- dog(403439) interleukin 2 receptor, beta
- domestic cat(101092622) interleukin 2 receptor, beta
- naked mole-rat(101726369) interleukin 2 receptor, beta
- Zebrafish(793920) interleukin 2 receptor, beta
- domestic guinea pig(100730639) interleukin 2 receptor, beta
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