IL10
interleukin 10
Synonyms:
CSIF, GVHDS, IL-10, IL10A, TGIF
Species:
Human IL10 (3586), Mouse Il10 (16153), Rat Il10 (25325), domestic guinea pig Il10 (100135553), domestic guinea pig Il10 (100715618), Zebrafish il10 (553957), chicken IL10 (428264), domestic cat IL10 (493683), dog IL10 (403628), cow IL10 (281246) ...More
UniProtKB ID:
Gene ID:
- Human(3586) Summary: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
- Mouse(16153) interleukin 10
- Rat(25325) interleukin 10
- domestic guinea pig(100135553) interleukin 10
- domestic guinea pig(100715618) interleukin 10
- Zebrafish(553957) interleukin 10
- chicken(428264) interleukin 10
- domestic cat(493683) interleukin 10
- dog(403628) interleukin 10
- cow(281246) interleukin 10
- Goat(100860746) interleukin 10
- Horse(100034187) interleukin 10
- sheep(443342) interleukin 10
- Domestic Rabbit(100008701) interleukin 10
- naked mole-rat(101708273) interleukin 10
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Canine IL10 / Interleukin-10 ELISA Kit, for serum, plasma and cell culture supernatants,
Species
dog