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Merck

HTR3D

5-hydroxytryptamine (serotonin) receptor 3D, ionotropic

Synonyms:
5HT3D
Species:
Human HTR3D (200909), domestic cat HTR3D (101090286)
UniProtKB ID:
Q70Z44, C9J2I6, J3QT78, Q495N5, Q495N6, Q7Z6B3
Gene ID:
  • Human(200909) Summary: The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
  • domestic cat(101090286) 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic

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Small Molecule - Antagonist

Product Number
Description
Species
A0590000
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0001534
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
M8046
Mifepristone, ≥98%,
Species
human, mouse, rat

Small Molecule - Inhibitor

Product Number
Description
Species
M8046
Mifepristone, ≥98%,
Species
human, mouse, rat