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Merck

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Synonyms:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Species:
UniProtKB ID:
Gene ID:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Antagonist

Product Number
Description
Species
1-Phenylpiperazine, ≥97.0%,
Species
mouse, rat
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Mifepristone, ≥98%,
Species
human, mouse, rat

Small Molecule - Inhibitor

Product Number
Description
Species
Mifepristone, ≥98%,
Species
human, mouse, rat