Skip to Content
Merck

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Synonyms:
5-HT2A, HTR2
Species:
UniProtKB ID:
Gene ID:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Description
Species
Clozapine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Clozapine Resolution Mixture, United States Pharmacopeia (USP) Reference Standard,
Species
human
Quetiapine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Quetiapine fumarate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Mifepristone, ≥98%,
Species
human, mouse, rat

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Mifepristone, ≥98%,
Species
human, mouse, rat