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Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Synonyms:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Species:
UniProtKB ID:
Gene ID:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

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Small Molecule - Antagonist

Product Number
Description
Species
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Mifepristone, ≥98%,
Species
human, mouse, rat

Small Molecule - Inhibitor

Product Number
Description
Species
Mifepristone, ≥98%,
Species
human, mouse, rat