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HRH1

histamine receptor H1

Synonyms:
H1-R, hisH1
Species:
UniProtKB ID:
Gene ID:
  • Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15465) histamine receptor H1
  • Rat(24448) histamine receptor H 1
  • naked mole-rat(101715481) histamine receptor H1
  • domestic cat(101088314) histamine receptor H1
  • domestic guinea pig(100135539) histamine receptor H1
  • chicken(100858928) histamine receptor H1
  • domestic guinea pig(100730517) histamine receptor H1
  • cow(281231) histamine receptor H1
  • dog(403813) histamine receptor H1
  • Zebrafish(735302) histamine receptor H1
  • Horse(100034110) histamine receptor H1
  • sheep(101121717) histamine receptor H1

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Small Molecule - Agonist

Product Number
Description
Species
Histamine, analytical standard,
Species
human
Histamine dihydrochloride, ≥99.0% (AT),
Species
human
Betahistine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Betahistine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Betahistine dihydrochloride, ≥98%,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Loratadine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Chlorpheniramine Maleate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Chlorpheniramine maleate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Cetirizine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Pheniramine maleate, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Histamine Receptor 1 Antibody, CT, Chemicon®, from rabbit,
Species Reactivity
bovine, mouse, rat
Application
ELISA
western blot

Small Molecule - Blocker

Product Number
Description
Species
Cinnarizine, European Pharmacopoeia (EP) Reference Standard,
Species
human