HPRT1
hypoxanthine phosphoribosyltransferase 1
Synonyms:
HGPRT, HPRT
Species:
Human HPRT1 (3251), Rat Hprt1 (24465), Zebrafish hprt1 (406259), chicken HPRT1 (395653), domestic guinea pig Hprt1 (100727355), naked mole-rat Hprt1 (101714108), sheep HPRT1 (100188975), cow HPRT1 (281229), Horse HPRT1 (100034149), domestic cat HPRT1 (768284) ...More
UniProtKB ID:
Gene ID:
- Human(3251) Summary: The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009]
- Rat(24465) hypoxanthine phosphoribosyltransferase 1
- Zebrafish(406259) hypoxanthine phosphoribosyltransferase 1
- chicken(395653) hypoxanthine phosphoribosyltransferase 1
- domestic guinea pig(100727355) hypoxanthine phosphoribosyltransferase 1
- naked mole-rat(101714108) hypoxanthine phosphoribosyltransferase 1
- sheep(100188975) hypoxanthine phosphoribosyltransferase 1
- cow(281229) hypoxanthine phosphoribosyltransferase 1
- Horse(100034149) hypoxanthine phosphoribosyltransferase 1
- domestic cat(768284) hypoxanthine phosphoribosyltransferase 1
- dog(442945) hypoxanthine phosphoribosyltransferase 1
- Domestic Rabbit(100126071) hypoxanthine phosphoribosyltransferase 1
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