HDAC3
histone deacetylase 3
Synonyms:
HD3, RPD3, RPD3-2
Species:
Human HDAC3 (8841), Mouse Hdac3 (15183), Rat Hdac3 (84578), fruit fly Hdac3 (44446), Zebrafish hdac3 (393965), cow HDAC3 (404125), chicken HDAC3 (395506), sheep HDAC3 (101107092), domestic guinea pig Hdac3 (100718985), dog HDAC3 (478040) ...More
UniProtKB ID:
Gene ID:
- Human(8841) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
- Mouse(15183) histone deacetylase 3
- Rat(84578) histone deacetylase 3
- fruit fly(44446) Histone deacetylase 3
- Zebrafish(393965) histone deacetylase 3
- cow(404125) histone deacetylase 3
- chicken(395506) histone deacetylase 3
- sheep(101107092) histone deacetylase 3
- domestic guinea pig(100718985) histone deacetylase 3
- dog(478040) histone deacetylase 3
- domestic cat(101100941) histone deacetylase 3
- naked mole-rat(101708680) histone deacetylase 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HDAC3 Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-HDAC3 Antibody, clone 3G6, clone 3G6, Upstate®, from mouse,
Species Reactivity
bovine, hamster, human, mouse
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot