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Merck

HAND2

heart and neural crest derivatives expressed 2

Synonyms:
DHAND2, Hed, Thing2, bHLHa26, dHand
Species:
UniProtKB ID:
Gene ID:
  • Human(9464) Summary: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. [provided by RefSeq, Jul 2008]
  • Mouse(15111) heart and neural crest derivatives expressed transcript 2
  • Rat(64637) heart and neural crest derivatives expressed 2
  • sheep(101120384) heart and neural crest derivatives expressed 2
  • cow(781874) heart and neural crest derivatives expressed 2
  • domestic guinea pig(100726553) heart and neural crest derivatives expressed 2
  • domestic cat(101091104) heart and neural crest derivatives expressed 2
  • chicken(395813) heart and neural crest derivatives expressed 2
  • Zebrafish(58150) heart and neural crest derivatives expressed transcript 2
  • dog(607431) heart and neural crest derivatives expressed 2
  • naked mole-rat(101712394) heart and neural crest derivatives expressed 2

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