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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonyms:
EPND, GluN2A, NMDAR2A, NR2A
Species:
UniProtKB ID:
Gene ID:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Product Number
Description
Species
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Species
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Species
human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human

Small Molecule - Antagonist

Product Number
Description
Species
Glycine, BioUltra, for molecular biology, ≥99.0% (NT),
Species
rat
Glycine, ACS reagent, ≥98.5%,
Species
rat
Glycine, suitable for electrophoresis, ≥99%,
Species
rat
Glycine, ReagentPlus®, ≥99% (HPLC),
Species
rat
Glycine, BioXtra, ≥99% (titration),
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NMDAR2A Antibody, Chemicon®, from rabbit,
Species Reactivity
fish, human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-NMDAR2A&B Antibody, pan, Chemicon®, from rabbit,
Species Reactivity
avian, guinea pig, human, mouse, rabbit, rat
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-NMDAR2A Antibody, ascites fluid, clone 2H9.24A6, Chemicon®,
Species Reactivity
frog, human, mouse, rabbit, rat
Application
western blot
Anti-NR2A Antibody, clone A12W, rabbit monoclonal, culture supernatant, clone A12W, Upstate®,
Species Reactivity
mouse, rat
Application
western blot
Anti-NMDAR2A Antibody, serum, Chemicon®,
Species Reactivity
fish, human, mouse, rat
Application
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
1,3-Diphenylguanidine, 97%,
Species
rat, mouse, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human