GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Synonyms:
GluN1, MRD8, NMDA1, NMDAR1, NR1
Species:
Human GRIN1 (2902), Mouse Grin1 (14810), Rat Grin1 (24408), naked mole-rat Grin1 (101720185), Horse GRIN1 (100059861), chicken GRIN1 (404296), sheep GRIN1 (443281), cow GRIN1 (100336579), domestic guinea pig Grin1 (100301989), dog GRIN1 (494007)
UniProtKB ID:
Gene ID:
- Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
- Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
- Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
- dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1
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Small Molecule - Agonist
Product Number
Description
Species
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NMDAR1 Splice Variant C2 Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-NMDAR1 Splice Variant C2 Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-NR1 Antibody, CT, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-NMDAR1 Antibody, (all splice variants), clone R1JHL, clone R1JHL, Chemicon®, from mouse,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-NMDAR1 Antibody, clone 1.17.2.6, rabbit monoclonal, clone 1.17.2.6, from rabbit, unconjugated,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot