GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
GluN1, MRD8, NMDA1, NMDAR1, NR1
Human GRIN1 (2902), Mouse Grin1 (14810), Rat Grin1 (24408), naked mole-rat Grin1 (101720185), Horse GRIN1 (100059861), chicken GRIN1 (404296), sheep GRIN1 (443281), cow GRIN1 (100336579), domestic guinea pig Grin1 (100301989), dog GRIN1 (494007)
- Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
- Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
- Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
- dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1
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Small Molecule - Agonist
Antibodies
Anti-NMDAR1 Splice Variant C2 Antibody, Chemicon®, from rabbit,
mouse, rat
immunohistochemistry
western blot
western blot
Anti-NR1 Antibody, CT, Upstate®, from mouse,
human, mouse, rat
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-NMDAR1 Splice Variant C2 Antibody, Chemicon®, from rabbit,
mouse, rat
immunohistochemistry
western blot
western blot
Anti-NMDAR1 Antibody, clone 1.17.2.6, rabbit monoclonal, clone 1.17.2.6, from rabbit, unconjugated,
human, mouse, rat
immunohistochemistry
western blot
western blot
Anti-NMDAR1 Antibody, (all splice variants), clone R1JHL, clone R1JHL, Chemicon®, from mouse,
human, mouse, rat
western blot