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Merck

GRIN1

glutamate receptor, ionotropic, N-methyl D-aspartate 1

Synonyms:
GluN1, MRD8, NMDA1, NMDAR1, NR1
Species:
UniProtKB ID:
Gene ID:
  • Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1

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Small Molecule - Agonist

Product Number
Description
Species
Taurine, ≥99%,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NMDAR1 Splice Variant C2 Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Anti-NR1 Antibody, CT, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-NMDAR1 Splice Variant C2 Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Anti-NMDAR1 Antibody, clone 1.17.2.6, rabbit monoclonal, clone 1.17.2.6, from rabbit, unconjugated,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-NMDAR1 Antibody, (all splice variants), clone R1JHL, clone R1JHL, Chemicon®, from mouse,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Taurine, ≥99%,
Species
human, rat