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Merck

GRIA4

glutamate receptor, ionotropic, AMPA 4

Synonyms:
GLUR4, GLUR4C, GLURD, GluA4
Species:
UniProtKB ID:
Gene ID:
  • Human(2893) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
  • Mouse(14802) glutamate receptor, ionotropic, AMPA4 (alpha 4)
  • Rat(29629) glutamate receptor, ionotropic, AMPA 4
  • sheep(443274) glutamate receptor, ionotropic, AMPA 4
  • domestic cat(101087003) glutamate receptor, ionotropic, AMPA 4
  • chicken(396137) glutamate receptor, ionotropic, AMPA 4
  • domestic guinea pig(100728256) glutamate receptor, ionotropic, AMPA 4
  • cow(529904) glutamate receptor, ionotrophic, AMPA 4
  • Horse(100061561) glutamate receptor, ionotropic, AMPA 4
  • dog(489427) glutamate receptor, ionotropic, AMPA 4
  • naked mole-rat(101698538) glutamate receptor, ionotropic, AMPA 4

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Small Molecule - Agonist

Product Number
Description
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human

Small Molecule - Antagonist

Product Number
Description
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Glutamate Receptor 4 Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human