GPX4
glutathione peroxidase 4
Synonyms:
GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx
Species:
Human GPX4 (2879), Mouse Gpx4 (625249), Rat Gpx4 (29328), domestic guinea pig Gpx4 (100730119), naked mole-rat Gpx4 (101708875), Thale Cress GPX4 (819427), chicken GPX4 (374056), domestic cat GPX4 (101095956), cow GPX4 (286809), Goat GPX4 (100860867)
UniProtKB ID:
Gene ID:
- Human(2879) Summary: Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008]
- Mouse(625249) glutathione peroxidase 4
- Rat(29328) glutathione peroxidase 4
- domestic guinea pig(100730119) glutathione peroxidase 4
- naked mole-rat(101708875) glutathione peroxidase 4
- Thale Cress(819427) glutathione peroxidase 4
- chicken(374056) glutathione peroxidase 4
- domestic cat(101095956) glutathione peroxidase 4
- cow(286809) glutathione peroxidase 4
- Goat(100860867) glutathione peroxidase 4
- sheep(101113149) glutathione peroxidase 4
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