GLRB
glycine receptor, beta
Synonyms:
HKPX2
Species:
Human GLRB (2743), Mouse Glrb (14658), Rat Glrb (25456), naked mole-rat Glrb (101709956), dog GLRB (475477), Horse GLRB (100061981), domestic cat GLRB (101088482), cow GLRB (281198), sheep GLRB (101109484), domestic guinea pig Glrb (100727431)
UniProtKB ID:
Gene ID:
- Human(2743) Summary: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
- Mouse(14658) glycine receptor, beta subunit
- Rat(25456) glycine receptor, beta
- naked mole-rat(101709956) glycine receptor, beta
- dog(475477) glycine receptor, beta
- Horse(100061981) glycine receptor, beta
- domestic cat(101088482) glycine receptor, beta
- cow(281198) glycine receptor, beta
- sheep(101109484) glycine receptor, beta
- domestic guinea pig(100727431) glycine receptor, beta
- chicken(422411) glycine receptor, beta
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Small Molecule - Allosteric Modulator
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Glycine Receptor Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot