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Merck

GABRB1

gamma-aminobutyric acid (GABA) A receptor, beta 1

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2560) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
  • Mouse(14400) gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
  • Rat(25450) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • Zebrafish(100331377) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • sheep(101122358) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • naked mole-rat(101717539) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic guinea pig(100719515) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic cat(101097640) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • dog(100687745) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • cow(282239) gamma-aminobutyric acid (GABA) A receptor, beta 1

Custom & Knockdown Gene Products

Small Molecule - Agonist

Product Number
Description
Species
Meprobamate, United States Pharmacopeia (USP) Reference Standard,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Zaleplon, United States Pharmacopeia (USP) Reference Standard,
Species
human
Zolpidem for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard,
Species
human
Diazepam for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Chlordiazepoxide hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Oxazepam for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Species
human
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Species
human