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Merck

GABRA2

gamma-aminobutyric acid (GABA) A receptor, alpha 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2555) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14395) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
  • Rat(289606) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • cow(282236) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • chicken(770511) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • naked mole-rat(101720776) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic guinea pig(100720796) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic cat(100286789) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Domestic Rabbit(100339376) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • sheep(101121265) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Horse(100061914) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • dog(482131) gamma-aminobutyric acid (GABA) A receptor, alpha 2

Custom & Knockdown Gene Products

Small Molecule - Agonist

Product Number
Description
Species
Meprobamate, United States Pharmacopeia (USP) Reference Standard,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Bromazepam, United States Pharmacopeia (USP) Reference Standard,
Species
human
Bromazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Lorazepam, United States Pharmacopeia (USP) Reference Standard,
Species
human
Oxazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Oxazepam for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
β-Naphthoflavone, ≥98%,
Species
2-Pyrrolidinone, ≥99%,
Species
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Species
human