G6PD
glucose-6-phosphate dehydrogenase
Synonyms:
G6PD1
Species:
Human G6PD (2539), Rat G6pd (24377), dog G6PD (481088), domestic cat G6PD (100270776), Horse G6PD (100059734), cow G6PD (281179), Zebrafish g6pd (570579), Domestic Rabbit G6PD (100328765), domestic guinea pig G6pd (100722769), naked mole-rat G6pd (101712640)
UniProtKB ID:
Gene ID:
- Human(2539) Summary: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(24377) glucose-6-phosphate dehydrogenase
- dog(481088) glucose-6-phosphate dehydrogenase
- domestic cat(100270776) glucose-6-phosphate dehydrogenase
- Horse(100059734) glucose-6-phosphate dehydrogenase
- cow(281179) glucose-6-phosphate dehydrogenase
- Zebrafish(570579) glucose-6-phosphate dehydrogenase
- Domestic Rabbit(100328765) glucose-6-phosphate dehydrogenase
- domestic guinea pig(100722769) glucose-6-phosphate dehydrogenase
- naked mole-rat(101712640) glucose-6-phosphate dehydrogenase
- sheep(443211) glucose-6-phosphate dehydrogenase
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