FUS
fused in sarcoma
ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS
Human FUS (2521), Mouse Fus (233908), Rat Fus (317385), chicken FUS (414144), Zebrafish fus (394058), fruit fly fus (44095), domestic cat FUS (101088901), dog FUS (479778), sheep FUS (101104799), cow FUS (280796) ...More
- Human(2521) Summary: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]
- Mouse(233908) fused in sarcoma
- Rat(317385) fused in sarcoma
- chicken(414144) fused in sarcoma
- Zebrafish(394058) fusion (involved in t(12;16) in malignant liposarcoma)
- fruit fly(44095) fusilli
- domestic cat(101088901) fused in sarcoma
- dog(479778) fused in sarcoma
- sheep(101104799) fused in sarcoma
- cow(280796) fused in sarcoma
- naked mole-rat(101716667) fused in sarcoma
- domestic guinea pig(100734300) fused in sarcoma
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