FLNA
filamin A, alpha
Synonyms:
ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
Species:
Human FLNA (2316), Mouse Flna (192176), Rat Flna (293860), domestic guinea pig Flna (100725162), Zebrafish flna (562529), chicken FLNA (395261), naked mole-rat Flna (101702004), Zebrafish flna (100534866), sheep FLNA (101120390), dog FLNA (481084) ...More
UniProtKB ID:
Gene ID:
- Human(2316) Summary: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
- Mouse(192176) filamin, alpha
- Rat(293860) filamin A, alpha
- domestic guinea pig(100725162) filamin A, alpha
- Zebrafish(562529) filamin A, alpha (actin binding protein 280)
- chicken(395261) filamin A, alpha
- naked mole-rat(101702004) filamin A, alpha
- Zebrafish(100534866) filamin A, alpha
- sheep(101120390) filamin A, alpha
- dog(481084) filamin A, alpha
- Domestic Rabbit(100328754) filamin A, alpha
- cow(281165) filamin A, alpha
- domestic cat(101082637) filamin A, alpha
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Filamin antibody,Mouse monoclonal, clone PM6/317, purified from hybridoma cell culture,
Species Reactivity
bovine, canine, hamster, human, monkey
Application
immunofluorescence
western blot
western blot
Anti-Filamin A Antibody, clone TI10, ascites fluid, clone TI10, Chemicon®,
Species Reactivity
bovine, human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Filamin A Antibody, clone PM6/317, ascites fluid, clone PM6/317, Chemicon®,
Species Reactivity
chicken, guinea pig, human, mouse, rabbit, rat
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot