FGFR1OP
FGFR1 oncogene partner
Synonyms:
FOP
Species:
Human FGFR1OP (11116), Mouse Fgfr1op (75296), Rat Fgfr1op (365103), sheep FGFR1OP (101115039), domestic cat FGFR1OP (101099885), dog FGFR1OP (612453), Zebrafish fgfr1op (415215), chicken FGFR1OP (421568), domestic guinea pig Fgfr1op (100728960), cow FGFR1OP (506246)
UniProtKB ID:
Gene ID:
- Human(11116) Summary: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
- Mouse(75296) Fgfr1 oncogene partner
- Rat(365103) FGFR1 oncogene partner
- sheep(101115039) FGFR1 oncogene partner
- domestic cat(101099885) FGFR1 oncogene partner
- dog(612453) FGFR1 oncogene partner
- Zebrafish(415215) FGFR1 oncogene partner
- chicken(421568) FGFR1 oncogene partner
- domestic guinea pig(100728960) FGFR1 oncogene partner
- cow(506246) FGFR1 oncogene partner
- naked mole-rat(101707272) FGFR1 oncogene partner
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