ESX1
ESX homeobox 1
Synonyms:
ESX1L, ESXR1
Species:
Human ESX1 (80712), Mouse Esx1 (13984), domestic cat ESX1 (101082983), cow ESX1 (616174), domestic guinea pig Esx1 (101788333), sheep ESX1 (101118426), naked mole-rat Esx1 (101715761)
UniProtKB ID:
Gene ID:
- Human(80712) Summary: This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010]
- Mouse(13984) extraembryonic, spermatogenesis, homeobox 1
- domestic cat(101082983) ESX homeobox 1
- cow(616174) ESX homeobox 1
- domestic guinea pig(101788333) ESX homeobox 1
- sheep(101118426) ESX homeobox 1
- naked mole-rat(101715761) ESX homeobox 1
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