ERAP1
endoplasmic reticulum aminopeptidase 1
Synonyms:
A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ERAAP1, PILS-AP, PILSAP
Species:
Human ERAP1 (51752), Mouse Erap1 (80898), Rat Erap1 (80897), dog ERAP1 (488898), chicken ERAP1 (427122), naked mole-rat Erap1 (101706813), domestic guinea pig Erap1 (100724993), Domestic Rabbit ERAP1 (100352256), sheep ERAP1 (101110506), cow ERAP1 (514617) ...More
UniProtKB ID:
Gene ID:
- Human(51752) Summary: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
- Mouse(80898) endoplasmic reticulum aminopeptidase 1
- Rat(80897) endoplasmic reticulum aminopeptidase 1
- dog(488898) endoplasmic reticulum aminopeptidase 1
- chicken(427122) endoplasmic reticulum aminopeptidase 1
- naked mole-rat(101706813) endoplasmic reticulum aminopeptidase 1
- domestic guinea pig(100724993) endoplasmic reticulum aminopeptidase 1
- Domestic Rabbit(100352256) endoplasmic reticulum aminopeptidase 1
- sheep(101110506) endoplasmic reticulum aminopeptidase 1
- cow(514617) endoplasmic reticulum aminopeptidase 1
- Horse(100073224) endoplasmic reticulum aminopeptidase 1
- domestic cat(101083063) endoplasmic reticulum aminopeptidase 1
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