EHMT1
euchromatic histone-lysine N-methyltransferase 1
Synonyms:
EUHMTASE1, Eu-HMTase1, FP13812, GLP, GLP1, KMT1D, bA188C12.1
Species:
Human EHMT1 (79813), Mouse Ehmt1 (77683), Rat Ehmt1 (362078), sheep EHMT1 (101123545), Horse EHMT1 (100058869), domestic cat EHMT1 (101087111), domestic guinea pig Ehmt1 (100735478), cow EHMT1 (528606), dog EHMT1 (491224), chicken EHMT1 (417250)
UniProtKB ID:
Gene ID:
- Human(79813) Summary: The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(77683) euchromatic histone methyltransferase 1
- Rat(362078) euchromatic histone-lysine N-methyltransferase 1
- sheep(101123545) euchromatic histone-lysine N-methyltransferase 1
- Horse(100058869) euchromatic histone-lysine N-methyltransferase 1
- domestic cat(101087111) euchromatic histone-lysine N-methyltransferase 1
- domestic guinea pig(100735478) euchromatic histone-lysine N-methyltransferase 1
- cow(528606) euchromatic histone-lysine N-methyltransferase 1
- dog(491224) euchromatic histone-lysine N-methyltransferase 1
- chicken(417250) euchromatic histone-lysine N-methyltransferase 1
- naked mole-rat(101699104) euchromatic histone-lysine N-methyltransferase 1
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