EFNA1
ephrin-A1
Synonyms:
B61, ECKLG, EFL1, EPLG1, LERK-1, LERK1, TNFAIP4
Species:
Human EFNA1 (1942), Mouse Efna1 (13636), Rat Efna1 (94268), naked mole-rat Efna1 (101709969), dog EFNA1 (490431), sheep EFNA1 (101105624), domestic cat EFNA1 (101094570), cow EFNA1 (507319), domestic guinea pig Efna1 (100732408)
UniProtKB ID:
Gene ID:
- Human(1942) Summary: This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]
- Mouse(13636) ephrin A1
- Rat(94268) ephrin A1
- naked mole-rat(101709969) ephrin-A1
- dog(490431) ephrin-A1
- sheep(101105624) ephrin-A1
- domestic cat(101094570) ephrin-A1
- cow(507319) ephrin-A1
- domestic guinea pig(100732408) ephrin-A1
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