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Merck

DSPP

dentin sialophosphoprotein

Synonyms:
DFNA39, DGI1, DMP3, DPP, DSP, DTDP2
Species:
UniProtKB ID:
Gene ID:
  • Human(1834) Summary: This gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(666279) dentin sialophosphoprotein
  • Rat(25254) dentin sialophosphoprotein
  • cow(100337125) dentin sialophosphoprotein
  • chicken(776475) dentin sialophosphoprotein
  • domestic cat(101099202) dentin sialophosphoprotein
  • dog(100683557) dentin sialophosphoprotein
  • naked mole-rat(101724668) dentin sialophosphoprotein
  • domestic guinea pig(101789124) dentin sialophosphoprotein

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