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Merck

DSCR4

Down syndrome critical region gene 4

Synonyms:
DCRB, DSCRB
Species:
Human DSCR4 (10281)
UniProtKB ID:
P56555, Q4VB31
Gene ID:
  • Human(10281) Summary: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. This gene is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta. [provided by RefSeq, Jul 2008]

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