DRD4
dopamine receptor D4
Synonyms:
D4DR
Species:
Human DRD4 (1815), Mouse Drd4 (13491), Rat Drd4 (25432), naked mole-rat Drd4 (101708437), dog DRD4 (448805), domestic guinea pig Drd4 (100733356), dog DRD4 (607223), chicken DRD4 (423016)
UniProtKB ID:
Gene ID:
- Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
- Mouse(13491) dopamine receptor D4
- Rat(25432) dopamine receptor D4
- naked mole-rat(101708437) dopamine receptor D4
- dog(448805) dopamine receptor D4
- domestic guinea pig(100733356) dopamine receptor D4
- dog(607223) dopamine receptor D4
- chicken(423016) dopamine receptor D4
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Small Molecule - Precursor
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