Skip to Content
Merck

DRD4

dopamine receptor D4

Synonyms:
D4DR
Species:
UniProtKB ID:
Gene ID:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • dog(448805) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • chicken(423016) dopamine receptor D4

Custom & Knockdown Gene Products

Small Molecule - Agonist

Product Number
Description
Species
Apomorphine hydrochloride hemihydrate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Ropinirole hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Ropinirole for peak identification 1, European Pharmacopoeia (EP) Reference Standard,
Species
human
Ropinirole hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Ropinirole Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Promazine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Chlorpromazine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Chlorpromazine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Droperidol, European Pharmacopoeia (EP) Reference Standard,
Species
human
Promazine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
3,4-Dihydroxy-L-phenylalanine, ≥98% (TLC),
Species
mouse, human, rat