DPM2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
CDG1U
Human DPM2 (8818), Mouse Dpm2 (13481), Rat Dpm2 (29640), domestic cat DPM2 (101098016), cow DPM2 (523737), Zebrafish dpm2 (796295), chicken DPM2 (771539), domestic guinea pig Dpm2 (100725474), naked mole-rat Dpm2 (101716252), sheep DPM2 (101122767)
- Human(8818) Summary: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq, Jul 2008]
- Mouse(13481) dolichol-phosphate (beta-D) mannosyltransferase 2
- Rat(29640) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- domestic cat(101098016) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- cow(523737) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- Zebrafish(796295) dolichol-phosphate (beta-D) mannosyltransferase 2
- chicken(771539) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- domestic guinea pig(100725474) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- naked mole-rat(101716252) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- sheep(101122767) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
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