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Merck

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

Synonyms:
DNMT3A2, M.HsaIIIA
Species:
Human DNMT3A (1788), Mouse Dnmt3a (13435), Rat Dnmt3a (444984), sheep DNMT3A (100500776), Domestic Rabbit DNMT3A (100344715), cow DNMT3A (359716), domestic cat DNMT3A (100510798), Horse DNMT3A (100055881), dog DNMT3A (482996), naked mole-rat Dnmt3a (101718745) ...More
UniProtKB ID:
Q9Y6K1, E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9
Gene ID:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha

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Antibodies

Product Number
Description
Species Reactivity
Application
07-2050
Anti-DNMT3A2 Antibody, from rabbit,
Species Reactivity
human
Application
ELISA
immunocytochemistry
western blot