DNASE2
deoxyribonuclease II, lysosomal
Synonyms:
DNASE2A, DNL, DNL2
Species:
Human DNASE2 (1777), Rat Dnase2 (171575), dog DNASE2 (476697), cow DNASE2 (282218), sheep DNASE2 (101105493), domestic guinea pig Dnase2 (100728975), naked mole-rat Dnase2 (101716162), Zebrafish dnase2 (100000399), fruit fly DNase2 (5656872), domestic cat DNASE2 (101086631)
UniProtKB ID:
Gene ID:
- Human(1777) Summary: This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008]
- Rat(171575) deoxyribonuclease II, lysosomal
- dog(476697) deoxyribonuclease II, lysosomal
- cow(282218) deoxyribonuclease II, lysosomal
- sheep(101105493) deoxyribonuclease II, lysosomal
- domestic guinea pig(100728975) deoxyribonuclease II, lysosomal
- naked mole-rat(101716162) deoxyribonuclease II, lysosomal
- Zebrafish(100000399) deoxyribonuclease II, lysosomal
- fruit fly(5656872) Deoxyribonuclease 2
- domestic cat(101086631) deoxyribonuclease II, lysosomal
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