DKK2
dickkopf WNT signaling pathway inhibitor 2
Synonyms:
DKK-2
Species:
Human DKK2 (27123), Mouse Dkk2 (56811), Rat Dkk2 (295445), domestic guinea pig Dkk2 (100715224), naked mole-rat Dkk2 (101716025), Zebrafish dkk2 (792404), chicken DKK2 (422531), cow DKK2 (541161), dog DKK2 (478502), sheep DKK2 (101123633)
UniProtKB ID:
Gene ID:
- Human(27123) Summary: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
- Mouse(56811) dickkopf homolog 2 (Xenopus laevis)
- Rat(295445) dickkopf WNT signaling pathway inhibitor 2
- domestic guinea pig(100715224) dickkopf WNT signaling pathway inhibitor 2
- naked mole-rat(101716025) dickkopf WNT signaling pathway inhibitor 2
- Zebrafish(792404) dickkopf homolog 2 (Xenopus laevis)
- chicken(422531) dickkopf 2 homolog (Xenopus laevis)
- cow(541161) dickkopf homolog 2 (Xenopus laevis)
- dog(478502) dickkopf 2 homolog (Xenopus laevis)
- sheep(101123633) dickkopf 2 homolog (Xenopus laevis)
- domestic cat(101090100) dickkopf 2 homolog (Xenopus laevis)
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