DGUOK
deoxyguanosine kinase
Synonyms:
MTDPS3, dGK
Species:
Human DGUOK (1716), Mouse Dguok (27369), Rat Dguok (297389), chicken DGUOK (770922), Zebrafish dguok (100005067), domestic cat DGUOK (101083164), dog DGUOK (475791), naked mole-rat Dguok (101709356), sheep DGUOK (101114690), cow DGUOK (509834)
UniProtKB ID:
Gene ID:
- Human(1716) Summary: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(27369) deoxyguanosine kinase
- Rat(297389) deoxyguanosine kinase
- chicken(770922) deoxyguanosine kinase
- Zebrafish(100005067) deoxyguanosine kinase
- domestic cat(101083164) deoxyguanosine kinase
- dog(475791) deoxyguanosine kinase
- naked mole-rat(101709356) deoxyguanosine kinase
- sheep(101114690) deoxyguanosine kinase
- cow(509834) deoxyguanosine kinase
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