CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
Synonyms:
CP27, CTX, CYP27
Species:
Human CYP27A1 (1593), Mouse Cyp27a1 (104086), Rat Cyp27a1 (301517), chicken CYP27A1 (431683), Domestic Rabbit CYP27A1 (100348736), cow CYP27A1 (511960), dog CYP27A1 (610489)
UniProtKB ID:
Gene ID:
- Human(1593) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008]
- Mouse(104086) cytochrome P450, family 27, subfamily a, polypeptide 1
- Rat(301517) cytochrome P450, family 27, subfamily a, polypeptide 1
- chicken(431683) cytochrome P450, family 27, subfamily A, polypeptide 1
- Domestic Rabbit(100348736) sterol 26-hydroxylase, mitochondrial
- cow(511960) cytochrome P450, family 27, subfamily A, polypeptide 1
- dog(610489) cytochrome P450, family 27, subfamily A, polypeptide 1
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