CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
Synonyms:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
Species:
Human CYP19A1 (1588), Mouse Cyp19a1 (13075), Rat Cyp19a1 (25147), Goat CYP19A1 (100861413), Horse CYP19A1 (100009712), dog CYP19A1 (494003), chicken CYP19A1 (414854), Domestic Rabbit CYP19A1 (100328545), cow CYP19A1 (281740)
UniProtKB ID:
Gene ID:
- Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
- Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
- Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
- Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
- Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
- dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
- chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
- Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
- cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1
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