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Merck

COX5A

cytochrome c oxidase subunit Va

Synonyms:
COX, COX-VA, VA
Species:
Human COX5A (9377), Mouse Cox5a (12858), Rat Cox5a (252934), chicken COX5A (769735), sheep COX5A (100170667), dog COX5A (478370), cow COX5A (444878)
UniProtKB ID:
P20674, P30045, Q8TB65
Gene ID:
  • Human(9377) Summary: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008]
  • Mouse(12858) cytochrome c oxidase subunit Va
  • Rat(252934) cytochrome c oxidase, subunit Va
  • chicken(769735) cytochrome c oxidase subunit Va
  • sheep(100170667) cytochrome oxidase subunit Va
  • dog(478370) cytochrome c oxidase subunit Va
  • cow(444878) cytochrome c oxidase subunit Va

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