Skip to Content
Merck

CNTNAP1

contactin associated protein 1

Synonyms:
CASPR, CNTNAP, NRXN4, P190
Species:
Human CNTNAP1 (8506), Mouse Cntnap1 (53321), Rat Cntnap1 (84008), domestic cat CNTNAP1 (101099341), domestic guinea pig Cntnap1 (100719034), naked mole-rat Cntnap1 (101714103), dog CNTNAP1 (490960), chicken CNTNAP1 (428309), Zebrafish cntnap1 (386706), cow CNTNAP1 (540997) ...More
UniProtKB ID:
P78357
Gene ID:
  • Human(8506) Summary: The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009]
  • Mouse(53321) contactin associated protein-like 1
  • Rat(84008) contactin associated protein 1
  • domestic cat(101099341) contactin associated protein 1
  • domestic guinea pig(100719034) contactin associated protein 1
  • naked mole-rat(101714103) contactin associated protein 1
  • dog(490960) contactin associated protein 1
  • chicken(428309) contactin associated protein 1
  • Zebrafish(386706) contactin associated protein 1
  • cow(540997) contactin associated protein 1
  • sheep(101111565) contactin associated protein 1
  • Horse(100052467) contactin associated protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.