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Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

Synonyms:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Species:
UniProtKB ID:
Gene ID:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IKKα Antibody, clone 14A231, clone 14A231, Upstate®, from mouse,
Species Reactivity
human, monkey, mouse
Application
western blot

Proteins

Product Number
Description
Species
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
IKK Substrate Peptide, ,
Species
human