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Merck

CHRM4

cholinergic receptor, muscarinic 4

Synonyms:
HM4, M4R
Species:
UniProtKB ID:
Gene ID:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2, purified antibody, clone 17F10.2, Chemicon®,
Species Reactivity
monkey, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Species
human