CD1C
CD1c molecule
Synonyms:
BDCA1, CD1, CD1A, R7
Species:
Human CD1C (911), Domestic Rabbit CD1C (100009419), chicken CD1C (425801), cow CD1C (100141145), sheep CD1C (101116198), dog CD1C (488609), domestic cat CD1C (101080762), Horse CD1C (100056353)
UniProtKB ID:
Gene ID:
- Human(911) Summary: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
- Domestic Rabbit(100009419) CD1c molecule
- chicken(425801) CD1c molecule
- cow(100141145) CD1c molecule
- sheep(101116198) CD1c molecule
- dog(488609) CD1c molecule
- domestic cat(101080762) CD1c molecule
- Horse(100056353) CD1c molecule
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