CAV1
caveolin 1, caveolae protein, 22kDa
Synonyms:
BSCL3, CGL3, MSTP085, PPH3, VIP21
Species:
Human CAV1 (857), Mouse Cav1 (12389), Rat Cav1 (25404), naked mole-rat Cav1 (101726366), domestic guinea pig Cav1 (100718512), chicken CAV1 (373996), dog CAV1 (403980), domestic cat CAV1 (493668), Horse CAV1 (100055975), Goat CAV1 (100860749) ...More
UniProtKB ID:
Gene ID:
- Human(857) Summary: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
- Mouse(12389) caveolin 1, caveolae protein
- Rat(25404) caveolin 1, caveolae protein
- naked mole-rat(101726366) caveolin 1, caveolae protein, 22kDa
- domestic guinea pig(100718512) caveolin 1, caveolae protein, 22kDa
- chicken(373996) caveolin 1, caveolae protein, 22kDa
- dog(403980) caveolin 1, caveolae protein, 22kDa
- domestic cat(493668) caveolin 1, caveolae protein, 22kDa
- Horse(100055975) caveolin 1, caveolae protein, 22kDa
- Goat(100860749) caveolin 1, caveolae protein, 22kDa
- cow(281040) caveolin 1, caveolae protein, 22kDa
- sheep(445468) caveolin 1, caveolae protein, 22kDa
- Domestic Rabbit(100008837) caveolin 1, caveolae protein, 22kDa
- domestic guinea pig(100135639) caveolin 1, caveolae protein
- Zebrafish(323695) caveolin 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Caveolin-1 Antibody, phospho-specific (Tyr14), Chemicon®, from rabbit,
Species Reactivity
human, monkey, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot