CASP6
caspase 6, apoptosis-related cysteine peptidase
Synonyms:
MCH2
Species:
Human CASP6 (839), Mouse Casp6 (12368), Rat Casp6 (83584), dog CASP6 (487899), Zebrafish casp6 (552927), chicken CASP6 (395477), naked mole-rat Casp6 (101707090), domestic guinea pig Casp6 (100713360), cow CASP6 (538409), sheep CASP6 (101119820)
UniProtKB ID:
Gene ID:
- Human(839) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(12368) caspase 6
- Rat(83584) caspase 6
- dog(487899) caspase 6, apoptosis-related cysteine peptidase
- Zebrafish(552927) caspase 6, apoptosis-related cysteine peptidase
- chicken(395477) caspase 6, apoptosis-related cysteine peptidase
- naked mole-rat(101707090) caspase 6, apoptosis-related cysteine peptidase
- domestic guinea pig(100713360) caspase 6, apoptosis-related cysteine peptidase
- cow(538409) caspase 6, apoptosis-related cysteine peptidase
- sheep(101119820) caspase 6, apoptosis-related cysteine peptidase
- domestic cat(768261) caspase 6, apoptosis-related cysteine peptidase
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