CAPN9
calpain 9
Synonyms:
GC36, nCL-4
Species:
Human CAPN9 (10753), Mouse Capn9 (73647), Rat Capn9 (116694), dog CAPN9 (608044), Zebrafish capn9 (445107), chicken CAPN9 (421544), naked mole-rat Capn9 (101716648), domestic guinea pig Capn9 (100714689), Domestic Rabbit CAPN9 (100358896), domestic cat CAPN9 (101091479)
UniProtKB ID:
Gene ID:
- Human(10753) Summary: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(73647) calpain 9
- Rat(116694) calpain 9
- dog(608044) calpain 9
- Zebrafish(445107) calpain 9
- chicken(421544) calpain 9
- naked mole-rat(101716648) calpain 9
- domestic guinea pig(100714689) calpain 9
- Domestic Rabbit(100358896) calpain 9
- domestic cat(101091479) calpain 9
- Horse(100051319) calpain 9
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