CAPN3
calpain 3, (p94)
Synonyms:
CANP3, CANPL3, LGMD2, LGMD2A, nCL-1, p94
Species:
Human CAPN3 (825), Mouse Capn3 (12335), Rat Capn3 (29155), naked mole-rat Capn3 (101707543), domestic guinea pig Capn3 (100735679), sheep CAPN3 (443038), Domestic Rabbit CAPN3 (100008726), domestic cat CAPN3 (101081304), cow CAPN3 (281663), dog CAPN3 (487518)
UniProtKB ID:
Gene ID:
- Human(825) Summary: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]
- Mouse(12335) calpain 3
- Rat(29155) calpain 3
- naked mole-rat(101707543) calpain 3, (p94)
- domestic guinea pig(100735679) calpain 3, (p94)
- sheep(443038) calpain 3, (p94)
- Domestic Rabbit(100008726) calpain 3, (p94)
- domestic cat(101081304) calpain 3, (p94)
- cow(281663) calpain 3, (p94)
- dog(487518) calpain 3, (p94)
- chicken(423233) calpain 3, (p94)
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