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Merck

CA9

carbonic anhydrase IX

Synonyms:
CAIX, MN
Species:
UniProtKB ID:
Gene ID:
  • Human(768) Summary: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jul 2008]
  • Zebrafish(566612) carbonic anhydrase IX
  • chicken(770004) carbonic anhydrase IX
  • dog(611933) carbonic anhydrase IX
  • domestic cat(101092802) carbonic anhydrase IX
  • Horse(100055579) carbonic anhydrase IX
  • cow(511923) carbonic anhydrase IX
  • sheep(101115682) carbonic anhydrase IX
  • domestic guinea pig(100729644) carbonic anhydrase IX
  • naked mole-rat(101722784) carbonic anhydrase IX

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ELISA

Product Number
Description
Species
Human Carbonic Anhydrase IX ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Sulfanilamide, puriss. p.a., ≥98% (calc. to the dried substance),
Species
human, mouse
Sulfanilamide, ≥98%,
Species
human, mouse