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Merck

BTN3A3

butyrophilin, subfamily 3, member A3

Synonyms:
BTF3
Species:
Human BTN3A3 (10384), chicken BTN3A3 (101668208), chicken BTN3A3 (101751667), sheep BTN3A3 (101103275), cow BTN3A3 (786760)
UniProtKB ID:
O00478, B4DWI7, E9PCP5
Gene ID:
  • Human(10384) Summary: The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]
  • chicken(101668208) butyrophilin, subfamily 3, member A3
  • chicken(101751667) butyrophilin, subfamily 3, member A3
  • sheep(101103275) butyrophilin, subfamily 3, member A3
  • cow(786760) butyrophilin, subfamily 3, member A3

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